GEN-RWD Sandbox: bridging the gap between hospital data privacy and external research insights with distributed analytics

Abstract Background Artificial intelligence (AI) has become a pivotal tool in advancing contemporary personalised medicine, with the goal of tailoring treatments to individual patient conditions.This has heightened the demand for access to diverse data from clinical practice and daily life for research, posing challenges due to the sensitive Embroi

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New light in flavin autofluorescence

Our attention was captured by the interesting debate on the identification of lipofuscins, lipofuscin-like lipopigments, or flavins as the responsible for intracellular autofluorescence Sports Overtops (AF) detected in epithelial cancer stem cells when exciting at 480-490 nm.Evidence was provided leading to ascribe AF emission to flavins accumulati

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